Inter Milan were held to a draw by Sampdoria, who came from behind twice to earn a point.
Federico Dimarco smashed a free-kick into the top corner, but Maya Yoshida, an ex-Southampton defender, equalised.
Lautaro Martinez then finished off a slick Inter counter-attack on the stroke of halftime, before Tommaso Augello smashed in a left-footed volley after the break.
After three games this season, Sampdoria is still winless.
Inter dropped points for the first time this season after two consecutive victories under Simone Inzaghi.
Napoli kept their perfect record intact on Saturday by defeating winless Juventus, who were playing their first game since the departure of forward Cristiano Ronaldo to Manchester United.