Sunderland University has been hit by “extensive IT disruption” which has “all the hallmarks of a cyber-attack”.
Telephone, website, and IT systems are down, but face-to-face instruction will continue as far as possible, according to the statement.
The university is collaborating with police and other agencies to determine what happened.
“We take the security of our systems very seriously and will work to resolve the situation as soon as possible,” said a spokesperson.
Newcastle and Northumbria Universities were targeted by hackers in September last year as the National Cyber Security Centre warned of a spike in attacks on educational institutions.